Botulinum toxin is a product produced by naturally occurring
Clostridium botulinum bacteria. This bacteria is found in soil and
marine sediments and can produce harmful neurotoxin botulinum toxin.
Botulinum toxin is a ‘blocking agent’ which inhibits the release
of certain neurotransmitters, specifically acetylcholine, from the
endings of the motor nerves. There are about eight types of botulinum
toxin named from type A to H. Botulinum toxin type A and botulinum
toxin type B are majorly used in cosmetic procedures for the
treatment of various facial conditions, its commercially marketed
under the brand name Botox. Botulinum toxin type A and B are also
used in medical applications for treatment of various diseases such
as dystonia, chronic migraines, and spasticity.
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Botulinum Toxin Market: Drivers
Frequent approvals of novel botulinum toxin products for different
indications are expected to drive growth of the Botulinum toxin
market in near future. For instance, in 2016, Ipsen S.A. received the
U.S. Food and Drug Administration (FDA) approval for its Dysport
(abobotulinumtoxinA) injection indicated for the treatment of
pediatric lower limb (PLL) spasticity in children of age two years
and older. In 2017, company received the FDA approval for same
product to use in adults. In 2017, Allergan plc. received FDA
approval for BOTOX Cosmetic (OnabotulinumtoxinA) for new indication
in forehead lines, and previously the product has been approved for
the treatment of , crow's feet lines, and glabellar lines. With this
approval company has expanded the indication of its product in the
temporary improvement in the appearance of moderate to severe
forehead lines associated with frontalis muscle activity in adults.
Botulinum Toxin Market: Regional analysis
North
America is expected to hold a dominant position in the global
botulinum toxin market,
owing to increasing trend of cosmetic procedures in the region. For
instance, according to a report published by American Society of
Plastic Surgeons in 2016, around US$ 16.4 billion was spent on
cosmetic procedures in the U.S. and in 2017, around 7.2 million
botulinum injections were used in the U.S. for cosmetic procedures.
Increasing number of cosmetic procedures in the key region of North
America is expected to drive the growth of the botulinum toxin market
in near future. Furthermore, Asia Pacific is expected to show rapid
growth in botulinum toxin market, owing to increasing R&D and
approval of novel products in China. For instance, in January 2018,
Daewoong Pharmaceutical Co. Ltd., a Korean company, received approval
from the Chinese authorities to conduct clinical trials for botulinum
toxin Nabota in China.
Botulinum Toxin Market: Key Players
Key players operating in global botulinum toxin market includes Ipsen
group, Allergan Plc., Medytox Inc., Merz GmbH and Co. KGaA, US
Worldmed, LLC, Lanzhou Institute of Biological Products Co. Ltd.,
Revance Therapeutics, Inc., and Daewoong Pharmaceutical Co., Ltd.
Major players in market are involved in strategic collaborations to
develop new products. For instance, in February 2018, Mylan N.V. and
Revance Therapeutics, Inc. underwent strategic collaboration and
license agreement for the development and commercialization of a
proposed biosimilar to BOTOX (onabotulinumtoxinA). Furthermore, key
players are focusing on receiving approvals of its product in key
market to expand their presence in global market. For instance, in
February 2018, Medytox Inc. filed a new drug application with the
China Food and Drug Administration (CFDA) to its botulinum neurotoxin
product Meditoxin in China.
Botulinum Toxin Market: Market Taxonomy
The global botulinum toxin market has been segmented based on product
type, application, distribution channel, and geography:
By Product Type:
-
Botulinum Toxin Type A
-
Botulinum Toxin Type B
By Application:
-
Cosmetics
-
Dystonia
-
Chronic Migraines
-
Spasticity
-
Others
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